脂質異常症：中国での増大する健康問題

タイトル: The levels distribution of the serum lipids in Xinjiang adults, 2018

概要: ObjectiveTo analyze the prevalence and distribution characteristics of dyslipidemia in adult residents of Xinjiang Uygur Autonomous Region (Xinjiang), and to provide effective prevention and control measures for dyslipidemia. MethodsIn 2018, a total of 4865 permanent residents aged 18 years and above were investigated by multi-stage stratified cluster random sampling in 8 monitoring counties (cities and districts) in Xinjiang. Questionnaire survey and laboratory tests were conducted, and fasting venous blood was collected to detect the levels of TC, TG, HDL-C and LDL-C in serum. To analyze the difference of the detection results of relevant indexes in serum of different age, sex and urban and rural adults. ResultsThe prevalence of dyslipidemia in adults in Xinjiang was 48.35%, among which the prevalence of hypercholesterolemia(high TC), hypertriglyceridemia(high TG), high low-density lipoprotein cholesterol(high LDL-C) and low high-density lipoprotein cholesterol (low HDL-C)were 18.58%, 28.04%, 25.30% and 13.40%. In 2018, the serum TC level in Xinjiang adults was (4.46{+/-}0.91) mmol/L, and that in males and females was (4.42{+/-}0.89) and (4.49{+/-}0.92) mmol/L, respectively (t=-2.848, p < 0.05). The serum TC level of urban residents (4.57{+/-}0.93) mmol/L was higher than that of rural residents (4.38{+/-}0.89) mmol/L, and the difference was statistically significant (t=6.979, p < 0.001). The difference of serum TC levels in different age groups was statistically significant (F=199.389, p < 0.001). The serum TG level was (1.52{+/-}1.12) mmol/L, (1.64{+/-}1.31) in male and (1.43{+/-}0.93) mmol/L in female, (t=6.359, p < 0.001). The serum TG level of urban residents (1.66{+/-}1.33) mmol/L was higher than that of rural residents (1.43{+/-}0.94) mmol/L, and the difference was statistically significant (t=7.088, p < 0.001). There were significant differences in serum TG levels among different age groups (F=31.355, p < 0.001). Serum HDL-C level was (1.23{+/-}0.33) mmol/L, (1.14{+/-}0.32) in male and (1.29{+/-}0.33) mmol/L in female, (t=-16.033, p < 0.001). The serum HDL-C level of urban residents (1.25{+/-}0.34 mmol/L) was higher than that of rural residents (1.21{+/-}0.33 mmol/L), and the difference was statistically significant (t=4.298, p < 0.001). The difference of serum HDL-C level in different age groups was statistically significant (F=10.992, p < 0.001). Serum LDL-C level was (2.55{+/-}0.77) mmol/L, (2.54{+/-}0.76) in male and (2.55{+/-}0.78) mmol/L in female, (t=-0.426, p > 0.05). The serum LDL-C level of urban residents (2.58{+/-}0.82) mmol/L was higher than that of rural residents (2.53{+/-}0.74) mmol/L, and the difference was statistically significant (t=2.180, p < 0.05). There were significant differences in serum LDL-C levels among different age groups (F=121.679, p < 0.001). ConclusionThe prevalence of dyslipidemia in adults in Xinjiang is higher than the national level, the serum LDL-C level in men is lower than that in women, and the serum TC, TG and HDL-C levels are higher than that in women.