COVID-19に対するマスクの効果を評価する

タイトル: Measuring the fitted filtration efficiency of cloth masks, medical masks and respirators

概要: ImportanceMasks reduce transmission of SARS-CoV2 and other respiratory pathogens. Comparative studies of the fitted filtration efficiency of different types of masks of are few. ObjectiveTo describe the fitted filtration efficiency against small aerosols (0.02 - 1 {micro}m) of medical and non-medical masks and respirators when worn, and how this is affected by user modifications (hacks) and by overmasking with a cloth mask. DesignWe tested a 2-layer woven-cotton cloth mask of a consensus design, ASTM-certified level 1 and level 3 masks, a non-certified mask, KF94s, KN95s, an N95 and a CaN99. SettingClosed rooms with ambient particles supplemented by salt particles. Participants12 total participants; 21 - 55 years, 68% female, 77% white, NIOSH 1 to 10. Main Outcome and MeasureUsing standard methods and a PortaCount 8038, we counted 0.02-1{micro}m particles inside and outside masks and respirators, expressing results as the percentage filtered by each mask. We also studied level 1 and level 3 masks with earguards, scrub caps, the knot-and-tuck method, and the effects of braces or overmasking with a cloth mask. ResultsFiltration efficiency for the cloth mask was 47-55%, for level 1 masks 52-60%, for level 3 masks 60-77%. A non-certified KN95 look-alike, two KF94s, and three KN95s filtered 57-77%, and the N95 and CaN99 97-98% without fit testing. External braces and overmasking with a well-fitting cloth mask increased filtration, but earguards, scrub caps, and the knot-and-tuck method did not. LimitationsLimited number of masks of each type sampled; no adjustment for multiple comparisons. Conclusions and RelevanceWell-fitting 2-layer cotton masks filter in the same range as level 1 masks when worn: around 50%. Level 3 masks and KN95s/KF94s filter around 70%. External braces or overmasking with a cloth-mask-on-ties produced filtration around 90%. Only N95s and CaN99s, both of which have overhead elastic, performed close to the occupational health and safety standards for fit tested PPE (>99%), filtering at 97-99%, without fit testing. These findings inform public health messaging about relative protection from aerosols from different mask types and increase understanding of findings of studies of implementation of masks and respirators. Key PointsQuestion: How well do medical and non-medical masks filter aerosols when worn? Findings: Well-fitting 2-layer cotton masks, and level 1 medical masks were similar, both filtering around 50% of aerosols. Level 3 masks and KN95/KF94s were similar, filtering around 70%. N95s and CaN99s, without formal fit testing, filtered 97-98%. Meaning: Level 1 medical masks were not better than the well-fitting 2-layer cotton masks we tested. KN95/KF94s are not as efficient, when worn, as N95s and CaN99s. Overmasking and the use of external braces improve filtration: these are potentially useful strategies when N95s are not available. O_FIG O_LINKSMALLFIG WIDTH=155 HEIGHT=200 SRC="FIGDIR/small/24304429v1_ufig1.gif" ALT="Figure 1"> View larger version (42K): [email protected]@10f8d0borg.highwire.dtl.DTLVardef@1f4d7faorg.highwire.dtl.DTLVardef@18f76ae_HPS_FORMAT_FIGEXP M_FIG C_FIG