The Truth About Potatoes and Cancer Risk
Research reveals concerns over potato consumption and colon cancer links.
Yasaman Jamshidi-Naeini, Colby J. Vorland, Pranav Kapoor, Bailey Ortyl, Jocelyn Mineo, Luke Still, Korlu Sorsor, Shelby Rodney, Xander Tooze, Brent Flickinger, Beate Henschel, Stephanie L. Dickinson, David B. Allison
― 5 min read
Table of Contents
Trust in Nutrition science is not as strong as in other types of science. This is concerning because trust in science is based on how reliable it is. To make nutrition Research reliable, it is important that the quality of that research is checked. This means looking at how well the research is designed, run, analyzed, and reported. Researchers are trying to improve this trustworthiness by making raw Data available for others to check results. Trust in research can only grow if others can see and confirm findings.
Cancer Risk
Potatoes andPotatoes are a popular food eaten by many people around the world. They are ranked as the third most consumed crop. Because of this, it is essential to look into how eating potatoes might affect health, especially concerning diseases like colon and rectal cancer (CRC). An important report from 2020 said there is moderate evidence that eating more food, including potatoes, may increase the risk of CRC. However, it was unclear if just eating potatoes alone was linked to this risk. Although some reviews have been done on this topic, they didn’t thoroughly check if the research can be repeated or confirmed. Therefore, a plan is needed to look into the trustworthiness of nutritional research about potatoes and CRC.
Research Process
To find relevant Studies, researchers looked at recent systematic reviews and updated a previous review to include new studies. They created a search strategy using various databases to identify studies about potatoes and CRC risk. The studies were evaluated based on several criteria, including whether they focused on humans older than 18 and whether they analyzed the independent relationship between potatoes and CRC. Any studies that failed to meet these specific criteria were excluded.
Screening the Studies
A total of 18 studies were chosen for review. All of these studies were non-randomized, meaning they did not have control groups that could make it easier to identify cause-and-effect relationships. Most of the chosen studies were done in various countries and included different types of participants. They typically assessed potato consumption through questionnaires. In almost all studies, CRC was confirmed using reliable medical records.
Assessing Data and Reproducibility
To check if the findings could be repeated, the researchers attempted to contact the authors of the original studies for raw data. They reached out via email and phone to gather the data they needed to confirm the findings. Unfortunately, many authors did not respond. In some cases, authors had retired and were unable to assist. For the few studies where the researchers got access to raw data, they put their methods to the test. They examined whether the original results could be reproduced by following the same methods used in the studies.
Results of Reproducibility Assessment
From the 18 studies, they could only reproduce the results of one study entirely, while another study showed mixed results. This revealed a concerning trend in the field of nutrition research: reproducibility is low. Most of the studies they reviewed did not share their data publicly, making it hard for others to check the results. This lack of data sharing is a significant issue, as transparency is needed to build trust in scientific findings.
Why Is This Important?
The inability to reproduce or verify results adds to the doubt surrounding dietary guidelines and the relationship between food and health. With the evidence showing that many studies on potatoes and CRC are hard to confirm, it brings into question the accuracy of claims made in nutrition science. If researchers want people to trust their findings, they need to improve methods for sharing data and ensure robust reporting practices.
Common Problems in Studies
The reviewed studies mostly had issues with the way they measured food consumption and handled missing data. Many studies lacked clear procedures to address the quality of their research designs. This raises concerns about the conclusions drawn from these studies; if the study quality is poor, the results may not reflect reality.
Moving Forward
While this study highlights the deficiencies in current research on potatoes and CRC, it also opens the door for improvements. Researchers should be encouraged to preregister their studies and share their data publicly. By doing so, they can help future researchers repeat their findings or build upon them. Better transparency and verification can lead to a better understanding of how certain foods, like potatoes, may impact our health.
Call for Change in Nutrition Research
To strengthen the trust in nutritional science, it is crucial that studies focus on making their findings reproducible. This involves sharing data openly and using reliable methods when collecting and analyzing information. By following these steps, researchers can help build a stronger foundation for nutritional knowledge that everyone can trust.
Conclusion
In the field of nutrition science, trust can’t just be taken for granted; it has to be earned. As more efforts are made to ensure that studies are not only reported but can also be verified, we will see improvements in how nutrition science is perceived.
So, the next time you enjoy some crispy fries, you might just wonder about the research behind potatoes and health. Are we dealing with a hidden health risk, or is it just another day of enjoying a tasty treat? One thing is certain: the science behind our food is more complex than it seems. And in the world of science, while things may look good on the surface, it is crucial to dig a little deeper and check the facts if we want to keep our stomachs and minds satisfied.
Let’s hope that in the future, researchers will bring us better insights and clearer answers when it comes to our beloved sources of carbs! After all, who knew potatoes could stir up such a scientific debate?
Original Source
Title: Evaluating the Reproducibility and Verifiability of Nutrition Research: A Case Study of Studies Assessing the Relationship Between Potatoes and Colorectal Cancer
Abstract: BackgroundThe credibility of nutritional research is dependent on the rigor with which studies are conducted and the ability for independent assessment to be performed. Despite the importance of these, more work is needed in the field of nutrition to buttress the trustworthiness of nutrition research. ObjectiveTo develop and apply a process for evaluating the rigor, reproducibility, and verifiability of nutritional research, using the relationship between potato consumption and Colorectal cancer (CRC) as a case study. MethodsWe updated existing systematic reviews to include studies on potatoes and CRC, assessing their design, execution, and reporting quality. We attempted to reproduce and verify the results of included studies by requesting raw data from authors and following statistical methods as described in the publications. Rigor was evaluated using four different tools: ROBINS-E, STROBE-Nut, Newcastle-Ottawa scale, and additional criteria related to transparency. ResultsEighteen studies were included, none of which publicly share data. We managed to access data for only two studies, successfully reproducing and verifying the results for one. The majority of studies exhibited a high risk of bias, with significant limitations in reporting quality and methodological rigor. ConclusionsResearch on the relationship between potato consumption and CRC risk is insufficiently reproducible and verifiable, undermining the trustworthiness of its findings. This study highlights the need for improving transparency, data sharing, and methodological rigor in nutritional research. Our approach provides a model for assessing the credibility of research in other areas of nutrition.
Authors: Yasaman Jamshidi-Naeini, Colby J. Vorland, Pranav Kapoor, Bailey Ortyl, Jocelyn Mineo, Luke Still, Korlu Sorsor, Shelby Rodney, Xander Tooze, Brent Flickinger, Beate Henschel, Stephanie L. Dickinson, David B. Allison
Last Update: 2024-12-02 00:00:00
Language: English
Source URL: https://www.medrxiv.org/content/10.1101/2024.12.01.24318272
Source PDF: https://www.medrxiv.org/content/10.1101/2024.12.01.24318272.full.pdf
Licence: https://creativecommons.org/licenses/by/4.0/
Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.
Thank you to medrxiv for use of its open access interoperability.