Effective Pain Management for Ankle and Hindfoot Fractures
Study examines pain relief methods for ankle and hindfoot surgery patients.
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Ankle and hindfoot injuries are common and can make walking difficult. When these areas are fractured, it causes pain and limits movement. Treating pain before and after surgery is important, but using too much or too little medication can lead to problems like readmissions to the hospital and unhappy patients. While choosing Painkillers, safety for the patient should also be considered. Patients usually receive injections for pain during their hospital stay and switch to pills when they go home. It is important to select painkillers that manage pain properly while having few side effects.
Current Knowledge on Pain Management
There is limited information on the best ways to manage pain for ankle and hindfoot fractures in adults. Guidelines from health organizations recommend using acetaminophen as the first choice for pain relief. Other medications may be added based on the type and location of the fracture. For ankle fractures specifically, acetaminophen is often recommended first. If pain continues, codeine or non-steroidal anti-inflammatory drugs (NSAIDs) may be added with caution, especially for older patients. In some cases, morphine is given when pain is not controlled well.
Research has looked into creating specific pain management plans for ankle and foot fractures. Some studies have shown that fewer painkillers can still control pain well. Others have looked into patient satisfaction and how effective different pain control methods are.
Purpose of the Study
This study aimed to see how well common painkillers work for patients who had surgery for ankle and hindfoot fractures. We wanted to find out which medications relieve pain effectively and safely for patients leaving the hospital and one week after. The findings could help doctors choose the right painkillers for their patients.
Study Design
After getting the necessary approvals, the study began in June 2022 and included adults who experienced ankle or hindfoot fractures from June 2022 to July 2023. Those who could not give consent or had amputations were not included. Each patient gave written consent before joining the study. Information about the patients and the medications they received at discharge and one week later was collected.
To understand the data better, we looked at patients’ ages and recorded pain levels using a simple scale where 0 means no pain and 10 means severe pain. Patients were followed up after one and two weeks to check their pain levels and any bad effects from the medications.
Results
In almost a year, 54 patients with ankle or hindfoot fractures were part of the study-46 had ankle fractures, 7 had hindfoot fractures, and 1 had both. Most patients were male, and the average age was 46. The common reasons for injury were falls and road accidents. Pain levels recorded at one week after discharge averaged 3.2 and decreased to 2.0 by the second week.
After one week, about half of the patients reported no adverse effects from the painkillers. However, 54% experienced side effects or serious adverse events. By the second week, 70% reported no issues. No deaths were recorded during the study.
Pain Management Observations
When we looked at the medications given to patients, some combinations showed side effects and poor pain control. For instance, one combination of acetaminophen, tramadol, and Diclofenac resulted in several patients experiencing side effects alongside moderate pain. Another mix including naproxen, acetaminophen, and pregabalin also led to moderate pain and side effects.
Patients who took acetaminophen combined with orphenadrine faced significant side effects and struggled with pain. A combination of celecoxib and acetaminophen worked better for pain control but still caused some side effects such as constipation and nausea.
Interestingly, the use of diclofenac alone or with acetaminophen proved to be effective for pain control, with most patients reporting low pain levels.
Analysis of Side Effects and Pain Control
The study looked closely at different pain management methods. Using tramadol with acetaminophen managed pain well but had some side effects. Over time, it became clear that certain combinations were safer and more effective than others.
For example, etoricoxib paired with acetaminophen had no side effects and managed pain effectively. However, mixing etoricoxib with tramadol or diclofenac led to serious side effects. Diclofenac when given on its own, had good results without many harmful effects.
Conclusion
The findings highlight the importance of choosing the right pain management strategies for patients with ankle and hindfoot fractures. Some commonly prescribed combinations were not effective in managing pain and resulted in harmful side effects. On the other hand, targeted combinations like diclofenac and acetaminophen provided better pain control with fewer adverse effects.
This study informs healthcare providers about effective pain management while ensuring patient safety. By identifying which medications work best together, doctors can improve outcomes for individuals recovering from ankle and hindfoot fractures.
Limitations and Future Directions
Even though this study provides valuable insights, it has some limitations. It was conducted at a single hospital, which might limit how broadly the results can be applied. More extensive research across multiple centers would help confirm these findings.
Going forward, researchers should continue examining how different pain management strategies affect patient recovery. Understanding the specific side effects linked to various medication combinations will help enhance treatment and ensure a safer, more comfortable recovery for patients.
The current study serves as a stepping stone towards better pain management practices in orthopedic care, specifically for ankle and hindfoot injuries. By focusing on safe and effective treatments, healthcare providers can improve not only the quality of care but also the overall patient experience.
Title: Optimal and Safe Pain Management Approach in Ankle and Hindfoot Fractures: Improving Practitioner Decision
Abstract: BackgroundOver or sub-optimal analgesic treatment leads to undesired consequences and patient dissatisfaction. The study aims to assess the sub-optimal or optimal pain relief and safety of routinely prescribed oral analgesic(s) at discharge and 1-week post-discharge in ankle and foot fracture surgeries. MethodsThe ongoing prospective cohort study data on 54 ankle and hindfoot trauma fracture adult patients enrolled between June 2022 to July 2023 was analyzed. Post-surgery oral analgesics prescribed at hospital discharge and 1-week follow-up were stratified for assessing adverse events and pain (Visual Analogue Scale) at 1- and 2 weeks post-discharge. The relationship of age, gender, and comorbidity was analyzed by multiple logistic regression for adverse events and multiple linear regression for pain score. ResultsMedian pain scores at 1- and 2-week follow-ups were 3.2 (IQR=3.0) and 2 (IQR=2.0) respectively. Combinations of tramadol, acetaminophen with naproxen or diclofenac or orphenadrine; and naproxen, pregabalin, with acetaminophen seemed toxic with sub-optimal pain control. Similar results were for celecoxib combined with pregabalin and etoricoxib combined with diclofenac or tramadol. Acetaminophen alone was safe but occasionally showed intolerance. Etoricoxib or diclofenac alone or with acetaminophen was safe and showed better pain control in this cohort. A regression model was non-significant for a relationship between covariates and pain scores or adverse events. ConclusionCurrent data suggests that certain oral analgesics or their combinations are harmful with sub-optimal pain control while some are safe and effective. Choosing suitable analgesics or their combinations in specific fractures might reduce patient harm with optimal pain management.
Authors: Zehra Abdul Muhammad, T. Ahmad, Y. Mohib, R. Hussain, M. Umer
Last Update: 2023-12-09 00:00:00
Language: English
Source URL: https://www.medrxiv.org/content/10.1101/2023.12.08.23299738
Source PDF: https://www.medrxiv.org/content/10.1101/2023.12.08.23299738.full.pdf
Licence: https://creativecommons.org/licenses/by/4.0/
Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.
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