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New Method for Measuring Childhood Abdominal Fat

A study proposes an efficient way to measure fat in children using MRI.

― 6 min read


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Table of Contents

Childhood obesity is a major health issue worldwide, leading to various diseases and health challenges later in life. It is linked to serious conditions like diabetes and heart disease. One of the key concerns is the amount of fat in the body, particularly the fat located in the abdomen. This fat can be divided into two types: Visceral Fat, which surrounds the organs, and Subcutaneous Fat, which is located just under the skin. Understanding the amounts of these types of fat is important for monitoring health in children.

Importance of Fat Measurement

Visceral fat is considered more harmful than subcutaneous fat, as it is closely related to metabolic and cardiovascular diseases. By accurately measuring these fat types, we can improve diagnosis and treatment, helping to prevent obesity-related diseases. Magnetic Resonance Imaging (MRI) is the preferred method for measuring fat because it is safe and provides detailed images without using harmful radiation.

Current Techniques for Fat Measurement

Traditionally, MRI uses special sequences known as Dixon sequences to identify fat and water in the body. Common methods for measuring abdominal fat can be time-consuming and often need a skilled operator to ensure accuracy. One such method is a semi-automated system called AMRA Researcher. This system has been verified in several studies and is widely used. However, it can be costly and not very accessible for everyone.

Study Overview

This work studies a group of children aged 7 to 9 years, using MRI to analyze abdominal fat. The goal is to find a simpler, more cost-effective way to measure visceral fat and subcutaneous fat automatically. The researchers used a database of MRI images and applied a technique called Convolutional Neural Networks (CNNs) to analyze the data.

Methods Used

The process started with MRI scans of children, which produced images known as Dixon sequences. These images were processed to create what are called total intensity maps. CNNs were then employed to automatically measure the amounts of visceral and subcutaneous fat from these maps.

The measurements obtained from this method were compared to those from the AMRA Researcher system to determine how accurate and reliable the new method was. Statistical tests were used to analyze the data and ensure that the findings were trustworthy.

Results

The results showed that the new method of measuring fat was quite accurate when compared to the established AMRA Researcher system. There was a high level of correlation between the measurements from both systems, indicating that the new method could be a viable alternative to the more expensive option.

Significance of the Findings

Being able to accurately measure fat in children has significant implications for health. A reliable method that is also accessible could help in the early detection of obesity-related problems, allowing for timely intervention and prevention strategies. This is particularly crucial, given the rising rates of childhood obesity globally.

Discussion

Overweight and obesity during childhood can lead to serious health concerns, including diabetes and heart disease. Between the years 2000 and 2016, the number of overweight children aged 5 to 19 increased significantly. This increase in childhood obesity raises concerns about future health outcomes, as children with obesity are likely to remain obese into adulthood.

In Mexico, the prevalence of childhood obesity is particularly concerning. According to the body mass index (BMI) measurements, a large percentage of children aged 5 to 9 are considered overweight or obese. This disparity in body fat distribution also presents challenges, as individuals with higher visceral fat levels face greater health risks compared to those with similar amounts of subcutaneous fat.

Need for Accurate Measurement

For effective health management, it is essential to have precise and repeatable measurements of body fat distribution. While dual-energy X-ray absorptiometry has been used for body fat measurement, it has limitations, such as exposure to radiation and the inability to provide detailed images needed for differentiating between fat types. MRI does not have these drawbacks and thus is regarded as the gold standard for measuring body composition.

Despite the benefits of MRI, quantifying visceral and subcutaneous fat remains challenging, especially in children. Research is limited in this area, and existing semi-automated methods are often reliant on operator expertise, leading to inconsistencies.

Alternative Approaches

Different automatic methods have been developed in recent years, with varying degrees of success. Convolutional Neural Networks (CNNs) are particularly notable for their effectiveness in image analysis. These networks mimic the way humans recognize images and can autonomously learn features from the data they are trained on.

Recent studies have shown the potential of CNNs in analyzing medical images, including fat quantification in adults. However, less attention has been given to applying these methods in assessing childhood obesity, revealing a gap in current research.

New Methodology

The proposed automatic measurement approach involves using total intensity maps derived from the MRI data to train CNNs focusing on distinguishing between visceral and subcutaneous fat. The methodology is straightforward and involves fewer steps than traditional methods, making it less resource-intensive.

By focusing on a simple and efficient method, this approach holds promise for widespread application, offering an effective means of tackling childhood obesity issues.

Potential Impact

This accessible method for measuring abdominal fat could empower healthcare providers to better monitor children's health. Early identification of obesity risks enables parents and doctors to implement preventative measures, leading to healthier lifestyles and reduced rates of obesity-related diseases.

In particular, utilizing MRI technology combined with advanced CNN techniques can make fat quantification affordable and straightforward for many clinics, enhancing overall health outcomes in children.

Limitations and Future Work

While the findings are promising, some limitations exist in this study. The sample size was relatively small, and there were some disparities in the representation of different weight categories. Additionally, the method's reliance on Dixon sequences may have limited the data's scope.

Future research should focus on expanding the dataset to include more diverse samples and validating the methodology across various imaging settings and populations. This will demonstrate the method's robustness and reliability, paving the way for broader implementation.

Conclusion

In summary, this study presents an automatic and efficient method for measuring abdominal fat in children, leveraging MRI and CNN technology. This approach aims to provide an accessible tool for diagnosing and preventing obesity-related health issues among children. By improving the way we measure body composition, we can take steps toward better health outcomes and tackle the childhood obesity epidemic more effectively.

Original Source

Title: Automatic quantification of abdominal subcutaneous and visceral adipose tissue in children, through MRI study, using total intensity maps and Convolutional Neural Networks

Abstract: Childhood overweight and obesity is one of the main health problems in the world since it is related to the early appearance of different diseases, in addition to being a risk factor for later developing obesity in adulthood with its health and economic consequences. Visceral abdominal tissue (VAT) is strongly related to the development of metabolic and cardiovascular diseases compared to abdominal subcutaneous adipose tissue (ASAT). Therefore, precise and automatic VAT and ASAT quantification methods would allow better diagnosis, monitoring and prevention of diseases caused by obesity at any stage of life. Currently, magnetic resonance imaging is the standard for fat quantification, with Dixon sequences being the most useful. Different semiautomatic and automatic ASAT and VAT quantification methodologies have been proposed. In particular, the semi-automated quantification methodology used commercially through the cloud-based service AMRA R Researcher stands out due to its extensive validation in different studies. In the present work, a database made up of Dixon MRI sequences, obtained from children between 7 and 9 years of age, was studied. Applying a preprocessing to obtain what we call total intensity maps, a convolutional neural network (CNN) was proposed for the automatic quantification of ASAT and VAT. The quantifications obtained from the proposed methodology were compared with quantifications previously made through AMRA R Researcher. For the comparison, correlation analysis, Bland-Altman graphs and non-parametric statistical tests were used. The results indicated a high correlation and similar precisions between the quantifications of this work and those of AMRA R Researcher. The final objective is that the proposed methodology can serve as an accessible and free tool for the diagnosis, monitoring and prevention of diseases related to childhood obesity.

Authors: José Gerardo Suárez-García, Po-Wah So, Javier Miguel Hernández-López, Silvia S. Hidalgo-Tobón, Pilar Dies-Suárez, Benito de Celis-Alonso

Last Update: 2023-09-12 00:00:00

Language: English

Source URL: https://arxiv.org/abs/2309.06535

Source PDF: https://arxiv.org/pdf/2309.06535

Licence: https://creativecommons.org/licenses/by-sa/4.0/

Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.

Thank you to arxiv for use of its open access interoperability.

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