Latest Articles for Drug Development

Molecular simulations are transforming how scientists develop new drugs by analyzing molecular interactions.

DigiLoCs improves predictions in drug testing, enhancing safety and effectiveness.

Exploring new methods to enhance antibody treatments through machine learning approaches.

A dataset of 86 million molecules aids research in drug discovery and material science.

D3FG model improves drug design by focusing on functional groups and linkers.

CEST offers insights into protein forms and their vital biological roles.

Research focuses on senescent cells and their role in glioblastoma progression.

A new method combines protein sequence and shape for better mutation predictions.

A new method improves treatment effectiveness estimates for biomarker-positive patients.

Examining Hsp90's movement can lead to better cancer treatments.

Examining GPCRs and their role in cell signaling for improved drug therapies.

Examining the role of patents in pharmaceutical innovation and research.

Researchers developed a new assay to explore EHD4 protein activity.

AAontology refines amino acid scales for better protein research applications.

A look into how bacteria manage protein degradation for survival.

A new method improves protein structure analysis through HDX-MS.

Examining how AlphaFold predicts protein structures and its challenges.

This article assesses the strengths and weaknesses of pharmacometric models in drug trials.

K2060 may improve treatments for brain disorders related to NMDARs.

Research compares NLME model approaches for drug effect estimation.

Researchers improve cancer therapies by refining antibody targeting methods.

A look into how phosphorylation affects protein shape and function.

A machine learning approach improves predictions of particle dynamics in complex fluids.

Examining the connection between NLRP3 inflammasome and inflammation regulation.

New methods improve understanding of drug binding and effectiveness.

A new method enhances speed and accuracy of molecular interaction calculations.

Researchers develop methods to improve drug selection for individual cancer patients.

Explore how molecular dynamics simulations reveal protein behavior and interactions.

A novel hydrogel using DNA aptamers for efficient thrombin sensing.

This article explores how protein shapes affect their roles in biology.

Explore the vital role of protein structure in health and disease.

New layer improves molecule behavior predictions in drug development.

Research reveals key details about Zika virus protease for potential antiviral drugs.

Recent studies reveal key insights for developing treatments against the Zika virus.

Research reveals A22's effects on actin and MreB in cells.

Research uncovers dynamics of AaSiaP in binding sialic acids.

New techniques improve molecular dynamics and drug design sampling methods.

Examining the roles and challenges of IgG1 and IgG3 antibodies in therapy.

Examining alternatives to the traditional two-trials rule for drug approval.

Research aims to develop antiviral drugs targeting EV-D68's key enzyme.