Simple Science

Cutting edge science explained simply

What does "S100A9" mean?

Table of Contents

S100A9 is a protein that plays a role in the body's response to inflammation. It is found in certain cells, especially during stress or injury. This protein has been linked to various diseases, including those that affect the brain, such as Alzheimer's and Parkinson's.

Role in Neurodegenerative Diseases

Recent research shows that S100A9 can interact with other proteins related to neurodegenerative diseases. For example, it can affect how alpha-synuclein, a protein linked to Parkinson's, forms droplets and aggregates. These interactions suggest that S100A9 might influence the development of brain disorders by changing how these proteins behave.

Impact on Protein Aggregation

Studies have found that S100A9 can both promote and inhibit the formation of certain protein structures known as amyloid fibrils. These fibrils are associated with conditions like Alzheimer's and prion diseases. When S100A9 is present, it can change the way other proteins clump together, which could be significant for finding new treatments for these diseases.

Conclusion

S100A9 is an important protein in inflammation and may play a key role in the development of neurodegenerative diseases. By understanding how it interacts with other proteins, researchers hope to develop new ways to address these serious health issues.

Latest Articles for S100A9