What does "NET" mean?
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NETs, or Neutrophil Extracellular Traps, are web-like structures made by neutrophils, a type of white blood cell. These traps are part of the body's immune response and help to catch and kill harmful microbes like bacteria and fungi.
How do NETs work?
When neutrophils sense an infection or danger, they can release these traps. The traps are made of DNA and proteins that can trap germs and prevent them from spreading. By doing this, NETs help the body fight off infections.
Why are NETs important?
NETs play a key role in protecting the body from infections. However, if they are released too much or inappropriately, they can also cause problems. Excessive NET formation is linked to various diseases, including autoimmune diseases, where the body mistakenly attacks its own tissues.
NETs in health and disease
In conditions like lupus and rheumatoid arthritis, the presence of NETs can be higher than normal. This can contribute to inflammation and damage to healthy cells. Researchers are studying how NETs function to find new ways to treat these diseases.