What does "Dyskinesia" mean?
Table of Contents
Dyskinesia refers to involuntary movements that can occur, especially in people with Parkinson's disease. These movements, which can be erratic and uncontrolled, often arise as a side effect of medication used to treat Parkinson's.
Causes
In Parkinson's disease, the brain doesn't produce enough dopamine, a chemical that helps control movement. Medications like levodopa are used to increase dopamine levels, but long-term use can sometimes lead to dyskinesia. Factors such as age and gender may also play a role in the likelihood of developing these movements.
Types of Dyskinesia
There are different types of dyskinetic movements. They can include twisting, jerking, or other repetitive motions that disrupt normal activity. These abnormal movements are often more noticeable when the medication is at its peak effect.
Brain Activity
Research shows that certain brain cells in the striatum, which help control movement, become overactive in dyskinesia. These cells communicate with each other and with other parts of the brain. Changes in their activity can lead to the involuntary movements seen in patients.
Genetic Factors
Studies have looked at the genetic reasons why some people develop dyskinesia while others do not. Specific genetic variations have been linked to a higher risk, indicating that genetics might influence how a person reacts to Parkinson's treatments.
Management
While dyskinesia can be challenging, there are strategies to manage the symptoms. Adjusting medications or adding new treatments may help reduce the severity of involuntary movements. Ongoing research continues to look for better ways to understand and treat dyskinesia in Parkinson's disease.