What does "Coactivators" mean?

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Coactivators are proteins that help transcription factors, which are responsible for turning genes on and off. They work by assisting transcription factors when they need to promote the production of specific proteins in a cell.

These coactivators do not bind directly to DNA; instead, they interact with the transcription factors and other proteins in the cell to boost gene activity. This can influence many processes in the body, from how cells grow to how they respond to signals.

Coactivators can be important in many areas, including in cancer research. Some types of cancer cells rely heavily on specific coactivators to survive and grow. Understanding how coactivators work can help scientists find new ways to treat diseases by targeting these proteins.

Overall, coactivators play a key role in gene regulation and can have significant impacts on health and disease.