What does "Alpha-fetoprotein" mean?
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Alpha-fetoprotein (AFP) is a protein that is mainly produced by the liver in the early stages of fetal development. In adults, AFP levels are usually low. However, high levels of AFP can indicate certain health issues.
Role in Liver Health
AFP is often measured in patients with liver-related conditions. It can help in spotting liver cancer, especially hepatocellular carcinoma (HCC). Doctors may use AFP levels along with other tests to make better decisions about diagnosis and treatment.
Factors Affecting AFP Levels
Several factors can influence AFP levels in the body. Conditions like liver inflammation, cirrhosis, and hepatitis can lead to an increase in AFP. Thus, while high AFP levels can suggest cancer, they can also result from other liver problems.
Combination with Other Tests
To improve accuracy in diagnosing HCC, AFP is sometimes used alongside other markers, like PIVKA-II and AFP-L3. This combined approach can provide a clearer picture of liver health and help in timely diagnosis.
Conclusion
While AFP is a useful marker in assessing liver health, it is important to consider it alongside other tests and factors. Continuous research is needed to fully understand its potential and improve liver cancer detection methods.