Rising Dengue Fever Cases in Bangladesh
Dengue fever infections in Bangladesh have surged, driven by climate change and urban growth.
― 5 min read
Table of Contents
- Understanding Infection and Immunity
- Dengue in South and Southeast Asia
- Climate Change and Urbanization
- Objectives of the Study
- Data Sources
- Statistical Analysis
- Increased Cases from 2000 to 2022
- Seasonal Trends
- Growth Factor Analysis
- Impact of Weather on Dengue Cases
- Future Predictions
- Recommendations for Public Health Measures
- Conclusion
- Original Source
Dengue fever is a disease caused by a virus that is spread through the bites of infected mosquitoes, mainly the female Aedes mosquitoes, such as Aedes aegypti and Aedes albopictus. This disease is found in many countries, particularly in tropical and subtropical regions, including more than 125 countries around the world. The World Health Organization (WHO) reports that dengue Cases are on the rise globally, with an estimated 390 million infections each year, of which about 96 million are severe enough to be clinically diagnosed.
Understanding Infection and Immunity
Most people infected with dengue experience mild symptoms or none at all, and these infections usually lead to lifelong immunity against that specific serotype of the virus. However, if a person gets infected with a different serotype, it can lead to more severe forms of the disease, increasing the risk of complications and death.
Dengue in South and Southeast Asia
South and Southeast Asia are among the worst-hit areas for dengue fever, accounting for over half of all reported cases. In Bangladesh, the first official outbreak was recorded in the year 2000, and since then, dengue has been a constant health issue. In recent years, the number of cases has risen, with distinct seasonal patterns observed. Most cases are reported during the monsoon season from May to August and again in September to December, but unusual trends have emerged since 2014, including increased cases during the pre-monsoon season.
Climate Change and Urbanization
Changes in climate, including shifts in Rainfall, Temperature, and humidity, combined with rapid urban growth, are important factors contributing to the rise in dengue cases. These changes disrupt the natural environment, creating conditions that favor the spread of the dengue virus. The concern is that this could lead to dengue being transmitted year-round rather than just during specific seasons.
Objectives of the Study
This study aims to look at dengue cases in Bangladesh over two decades-2000 to 2010 and 2011 to 2022. Specifically, the goals include:
- Comparing the annual and monthly cases between the two decades.
- Identifying trends and seasonal patterns of dengue cases.
- Analyzing the impact of Weather conditions on dengue occurrences.
- Forecasting future dengue cases for the next decade.
Data Sources
The analysis uses data from the Directorate General of Health Services (DGHS) for reported cases of dengue from January 2000 to December 2022. It also includes weather data like temperature and rainfall from the Bangladesh Meteorological Department.
Statistical Analysis
The analysis covers the period from 2000 to 2022, focusing on the characteristics of dengue cases and deaths. Initial calculations included mean and standard deviation for each year and month. Comparisons were made between the two decades to see how cases, deaths, and weather conditions differed. Monthly changes were evaluated to understand growth trends in dengue cases.
To assess the impact of climate on dengue cases, a Generalized Linear Model (GLM) was created using weather data and reporting of cases. This model can help identify how temperature and rainfall influence the number of reported dengue cases.
Increased Cases from 2000 to 2022
Between 2000 and 2022, Bangladesh reported over 244,000 cases of dengue fever, with an average of over 10,000 cases each year. There was an increase in the number of infections, with cases in the second decade jumping more than eight times compared to the first decade. Deaths due to dengue also rose, but the case-fatality ratio (CFR) actually decreased, meaning that while more people were getting infected, the proportion of deaths was lower compared to earlier years.
Seasonal Trends
Data revealed that most dengue infections occurred during August, while February had the lowest number. The most significant rise in cases was noted after the introduction of new virus types, particularly in 2019 and 2022. The average temperature increased slightly over the years, and rainfall patterns showed a decrease in total annual rainfall but notable spikes during certain months, particularly early or late in the monsoon season.
Growth Factor Analysis
The growth factor analysis indicated that there was a significant increase in dengue cases in months leading up to the peak season from April to July. This suggests that effective interventions for mosquito control should begin in April to manage the increasing incidence of the disease.
Impact of Weather on Dengue Cases
The study showed that for every one-degree increase in temperature, dengue cases would increase by approximately 26%. Rainfall also played a major role; an additional centimeter of rainfall in the months leading up to the peak was found to increase cases by up to 17%. This indicates that weather conditions significantly influence how dengue spreads.
Future Predictions
Using a forecasting model, researchers predict that dengue cases will continue to rise in future years, mainly due to climate change and urbanization. The urgency for effective management strategies becomes even clearer as these trends indicate longer and more intense dengue seasons.
Recommendations for Public Health Measures
Given the findings, it is clear that a comprehensive approach is necessary to control dengue cases in Bangladesh. Involving local communities in efforts to eliminate mosquito breeding sites and increasing active surveillance for detecting cases are crucial steps. Health authorities must act promptly based on trends to control vector populations and prevent further spread of the disease.
Conclusion
Dengue fever remains a critical public health challenge in Bangladesh, with cases increasing alarmingly in recent decades. This study highlights the need for proactive measures, including better environmental management, community engagement, and timely interventions to address the factors driving dengue transmission. Maintaining awareness of climate impacts and urban growth will be vital in combating the disease effectively. With continuous monitoring and responsive action, there is hope for reducing the burden of dengue fever in the future.
Title: Two Decades of Endemic Dengue in Bangladesh (2000-2022): Trends, Seasonality, and impact of Temperature and Rainfall Patterns on transmission dynamics
Abstract: BackgroundThe objectives of this study were to compare the dengue virus (DENV) infection, deaths, case-fatality ratio, as well as meteorological parameters between the first and and the recent decade (2000-2010 vs. 2011-2022) and to understand the trends, seasonality, and impact of change of temperature and rainfall pattern on transmission dynamics of Dengue in Bangladesh MethodsFor the period 2000-2022, dengue cases and death data from Bangladeshs Ministry of Health and Family Welfares website, and meteorological data from the Bangladesh Meteorological Department were analyzed. Mann-Kendall and Sens slop tests were used for trends and variations and fitted a time series Poisson regression model to identify the impact of meteorological parameters on the incidence of dengue cases. A forecast of dengue cases was performed using an autoregressive integrated moving average model. ResultsOver the past 22 years, a total of 244,246 dengue cases were reported including 849 deaths (Case fatality ratio [CFR] =0.34%). The mean annual number of dengue cases increased eight-fold during the second decade, with 2216 cases during 2000-2011 vs. 18,321 during 2012-2022. The mean annual deaths have doubled (21 vs. 46) although the overall CFR had decreased to one-third (0.69 vs 0.24). Between the periods, the annual temperature increased by 0.49 {degrees}C, and rainfall decreased by 314 mm despite increasing unusual rainfall in the pre-and-post monsoon period. An increasing trend of dengue cases is observed with a much stiffer rise after 2018. Monthly mean temperature (Incidence risk ratio [IRR]: 1.26), first-lagged rainfall (IRR: 1.08), and second-lagged rainfall (IRR: 1.17) were significantly associated with monthly dengue incidence. ConclusionsThe increased local temperature and unusual rainfall might have contributed to the increased incidence of DENV infection in Bangladesh. Community engagement, vector control, and destruction of mosquito habitats are key to controlling dengue.
Authors: Najmul Haider, M. N. Hasan, I. Khalil, M. A. B. Chowdhury, M. Rahman, M. Asaduzzaman, M. Billah, L. A. Banu, M.-U. Alam, A. Ahsan, T. Traore, M. J. Uddin, R. Galizi, I. Russo, A. Zumla
Last Update: 2023-07-18 00:00:00
Language: English
Source URL: https://www.medrxiv.org/content/10.1101/2023.07.16.23292380
Source PDF: https://www.medrxiv.org/content/10.1101/2023.07.16.23292380.full.pdf
Licence: https://creativecommons.org/licenses/by/4.0/
Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.
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