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Cultivated Meat: A Sustainable Future for Food Production

Examining the environmental impacts of serum-free culture media in cultivated meat production.

― 6 min read


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Table of Contents

Meat production from livestock is a big factor in harming the environment. It contributes greatly to greenhouse gas emissions, uses a lot of land and water, and leads to issues like loss of biodiversity. As the world’s population grows, meat production is expected to rise by about 76% by 2050. This will worsen the environmental effects of raising animals for food.

Cultivated meat, which is made by growing animal cells in labs, is being looked at as a possible solution. This method aims to produce meat with less harm to the environment while also helping to meet future food needs. Studies show that the materials used to grow these cells make up a significant part of the total environmental impact. Thus, understanding the environmental effects of these growth materials is necessary for reducing the overall impacts of cultivated meat.

Currently, much of the cultivated meat is made using a culture medium that includes Fetal Bovine Serum (FBS). However, FBS has several problems. It raises ethical concerns because it comes from young cattle, and it can also contain harmful substances. Plus, its price can change a lot. Moving to a serum-free medium is essential for creating meat that is better for the environment and acceptable to consumers.

This study looked into current methods of producing serum-free food-grade culture media and their environmental impact. It also examined how these impacts might change as technology advances and production scales up. The goal was to find effective ways to reduce the environmental effects linked to these culture media.

Research Method

The study used a method called Life Cycle Assessment (LCA) to evaluate the environmental impact. This method analyzes the effects of a product from start to finish, including raw material production, product manufacturing, and waste.

Components of the Culture Medium

The culture medium studied is a base mixture developed from a commonly used medium called DMEM. This new medium is designed to replace animal-derived ingredients with food-grade components. To create a serum-free culture medium, the study used a method that brings together several types of organ cells to create a substitute for serum.

System Boundaries and Functional Units

The study's focus was on the manufacturing steps, from obtaining raw materials to producing the culture medium. The evaluation considered the materials needed to create 1 liter of the culture medium. Various steps in the process, including cleaning and waste disposal, were also included in this assessment.

Future Production Scenarios

The study explored future production scenarios, where it assumed that production would get about 700 times larger. This future model suggested more efficient methods like using stainless steel for equipment instead of disposable materials. It also looked into how different sources of electricity might affect the Environmental Impacts.

Data Collection

Data for the study came from IntegriCulture Inc. in Japan, which provided details about their culture medium production process. Additional literature was consulted to fill in gaps in the information.

Life Cycle Inventory

The study created an inventory of all the materials and energy used for producing 1 liter of culture medium. This inventory helped to identify the environmental impact for various materials and inputs, including electricity, raw materials, and waste.

Life Cycle Impact Assessment

The study used a specific impact assessment method that allows for understanding various environmental effects. It focused on eight key impact areas, including climate change, water use, and land use.

Current Production Impact

At the current scale, electricity outlined a significant portion of the environmental impact. In particular, it played a major role in areas like climate change and resource consumption. Animal-based ingredients also had a notable impact, particularly in water use and land consumption. Another significant factor was the use of disposable materials, which contributed to waste and increased the total environmental footprint.

Electricity consumption was largely driven by the need to control the cell culture environment and sterilize equipment. Reducing this electricity and the use of disposables could lessen the overall impact. For example, as technology advances, larger devices may replace smaller individual pieces of equipment, enabling easier sterilization and reducing energy needs.

Future Production Impact

For future production scenarios, the study considered how using different electricity sources will affect the environmental outcome. It projected an increase in electricity use due to the anticipated growth in production capacity. However, the impacts could vary depending on the type of energy used.

The study looked at scenarios that included renewable energy sources like solar and wind power. Using these cleaner energy sources generally helps lower the environmental impact, especially regarding climate change. However, increased land use associated with renewable energy generation could offset some benefits, as it may compete with land previously used for other purposes.

To combat this, the study suggested placing solar panels on rooftops or using urban spaces for energy production, which could minimize land use conflicts.

Components of the Culture Medium

The analysis revealed that the serum substitute components had a bigger impact than the basal medium ingredients in most scenarios. As the production moves to a larger scale, the proportion of the environmental impact from basal medium ingredients is expected to grow.

The study highlighted the need to find more sustainable sources for basal medium components, suggesting that ingredients from plants or algae could offer lower environmental impacts than current sources.

Sensitivity Analysis

Recognizing that laboratory settings can be variable, a sensitivity analysis was done to see how changes in the use of disposable items could affect environmental impacts. Results showed that reducing the use of disposables would significantly lower the environmental impact across all areas measured.

Study Limitations and Future Directions

The research faced limitations, including the fact that it only focused on one type of culture medium and one company's production method. Future studies should compare other culture media and methods to get a more comprehensive view of their environmental impacts.

Additionally, conducting a full life cycle assessment of the entire cultivated meat production process, including steps beyond culture medium production, should be a priority for future research efforts.

Conclusion

The shift toward cultivated meat has the potential to reduce the environmental burden of meat production significantly. However, to realize these benefits, it’s crucial to develop sustainable production methods and materials for culture media. This study underscores the importance of finding alternatives to animal-derived components and highlights the impact of energy consumption, pushing for smarter uses of renewable energy. Addressing these challenges could lead to a more sustainable future for food production.

Original Source

Title: Environmental Impacts of Serum-free Food-grade and Complex Culture Medium Production for Cultivated Meat

Abstract: Cultivated meat is an alternative meat produced via cell culture. The culture medium accounts for most of the environmental impact of cultivated meat production. This study quantitatively evaluated and analyzed the environmental impact of serum-free food-grade and complex culture medium production for cultivated meat by performing a life cycle assessment (LCA) based on activity data at the laboratory scale. In addition, specific measures were proposed to reduce the environmental impact further. LCAs were performed at current and future production scales. This study also evaluated the impact of multiple electricity sources on the environmental impact of culture-medium production. Expendables at the current scale, as well as electricity and animal-derived materials at both scales, are hotspots in the environmental impact of this culture-medium production. Among these components, the production of serum substitutes accounts for most of the environmental impact. As the scale shifts, the environmental impacts are expected to decrease by 11.3%-93.2% in all impact categories. As the composition of electricity sources changed, the impact on certain categories decreased. However, as the share of renewable energy increased, the impact on land use also increased significantly. This study promotes the practical application of new culture media for low-cost and low-environment-impact cultivated meat. Graphical abstract O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=108 SRC="FIGDIR/small/611339v1_ufig1.gif" ALT="Figure 1"> View larger version (43K): [email protected]@199eb86org.highwire.dtl.DTLVardef@35d02aorg.highwire.dtl.DTLVardef@f581d0_HPS_FORMAT_FIGEXP M_FIG C_FIG SYNOPSIS. This study evaluates the environmental impact of culture-medium production for cultivated meat and reports that electricity, animal-derived materials, and expendables are hotspots of this impact.

Authors: Naoki Yoshikawa, N. Takenaka, K. H. Mitsui, K. Kunimasa, K. Kawajiri, C. Kayo

Last Update: 2024-09-10 00:00:00

Language: English

Source URL: https://www.biorxiv.org/content/10.1101/2024.09.05.611339

Source PDF: https://www.biorxiv.org/content/10.1101/2024.09.05.611339.full.pdf

Licence: https://creativecommons.org/licenses/by-nc/4.0/

Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.

Thank you to biorxiv for use of its open access interoperability.

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