Tackling Tuberculosis in Paraguay's Vulnerable Communities
Exploring the ongoing TB crisis among Indigenous and imprisoned populations in Paraguay.
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Table of Contents
Tuberculosis (TB) is a serious infectious disease that affects many people around the world. Despite being preventable and treatable, TB still causes a lot of deaths every year. In 2022, around 1.3 million people died from TB globally. In the Americas, the number of TB cases has increased in recent years, including in Paraguay. Between 2010 and 2022, TB cases in Paraguay rose from 42 to 46 per 100,000 people.
Recently, the COVID-19 pandemic has affected how TB cases are found and treated. This raises questions about why the number of recorded TB cases is increasing and which groups of people are at most risk.
Who is Affected by TB?
TB mainly affects people living in poverty and those who do not have good access to health care. In some places, such as Prisons, the rate of TB is much higher than in the general population. For example, in some countries, people in prison are nine times more likely to get TB. This is due to crowded living conditions, limited health care access, and other challenges faced in these environments.
In the Americas, Indigenous people are also at greater risk for TB. Historical issues like displacement and long-standing barriers to health care have contributed to this problem. TB rates among Indigenous communities in South America became a serious issue after European colonization and have been made worse by ongoing social and economic challenges.
In Paraguay, previous studies show that Indigenous people have very high rates of TB. In some rural areas, the incidence was measured at 335.3 cases per 100,000 in 2016. Additionally, over a quarter of Paraguayans live below the poverty line, which could increase their risk of TB.
Understanding the Numbers
Data from the Paraguay National Program for Tuberculosis Control shows that between 2018 and 2022, there were 13,725 new cases of TB reported. Among these, 1,743 cases were found in Indigenous populations, and 2,331 cases were found in people in prison. It is important to note that rates of TB notifications varied widely across different regions in Paraguay.
For instance, the department of Boquerón saw the largest increase in TB cases, while Alto Paraguay had the largest decrease. The Chaco region, home to a large Indigenous population, reported a high number of TB cases.
The Role of Prisons
In Paraguay, prisons are major sites for TB outbreaks. Reports indicate that the percentage of TB cases occurring among imprisoned individuals increased significantly from 2009 to 2018. In some areas, more than half of TB cases were found among people in prison. Most of these cases were in men.
The use of a special treatment method called Directly Observed Therapy (DOT) is crucial for TB success rates, especially for those in prison. DOT means a health worker ensures the patient takes their TB medicine regularly. This approach has shown to improve treatment results.
Advances in Diagnosis
Molecular tests, which are advanced methods for diagnosing TB, have become more common in Paraguay. Between 2018 and 2022, the use of GeneXpert, a rapid diagnostic tool, increased significantly. While access to testing has improved overall, Indigenous populations still lag behind in receiving these tests.
This is crucial as timely diagnosis helps in reducing transmission and improving treatment outcomes. In fact, all reported TB cases among Indigenous people in one department used GeneXpert testing.
Treatment Outcomes
Out of the total TB cases reported during the study period, 60% of patients successfully completed their treatment. Some patients were lost to follow-ups, some died, and a few experienced treatment failures. It is noted that the most serious challenges for successful treatment included co-infection with HIV and alcohol use disorders.
When analyzing factors that impacted treatment success, it was found that being part of a higher education group, being Indigenous, and being on DOT helped improve treatment outcomes. Conversely, older age and being co-infected with HIV were linked to lower chances of treatment success.
Addressing the Challenges
Despite improvements in diagnosing and treating TB, the disease remains a significant public health challenge in Paraguay. Marginalized groups like Indigenous people and those in prison face the biggest risks and challenges regarding TB.
Recent health programs have aimed to enhance TB care among these vulnerable populations. The NPTC has worked to provide better access to diagnosis and treatment, especially in the Chaco Region.
It is crucial to continue expanding the availability of TB testing and Treatments to the most impacted communities. This would help in reducing the high rates of TB that persist among these groups.
The Importance of Awareness
Awareness about TB and its risks is also essential for controlling the disease. Public health campaigns are needed to inform populations about TB prevention, symptoms, and treatment options. Effective communication can help ensure that those at risk know how to seek care and get treated early.
Conclusion
In summary, TB remains a major public health issue in Paraguay, particularly among vulnerable groups such as Indigenous people and incarcerated individuals. Through the use of rapid diagnostic tests and effective treatment programs like DOT, progress can be made in controlling and reducing the incidence of TB.
It is important to maintain focus on expanding access to health care services, improving awareness, and addressing social and economic factors that contribute to the risk of TB. By focusing efforts on the populations most affected, Paraguay can work towards reducing the burden of this disease and improving health outcomes for all.
Title: The concentration of tuberculosis within Paraguay's incarcerated and Indigenous populations, 2018-2022
Abstract: While incidence of tuberculosis (TB) has decreased globally, in Paraguay, considered a medium-incidence country by the WHO, TB incidence has increased slightly from 42 per 100,000 in 2010 to 46 per 100,000 in 2022. We conducted a retrospective study of TB cases notified to the Paraguay National Program for Tuberculosis Control (NPTC) from 2018 to 2022 and quantified trends in specific populations identified as vulnerable. Of the 13,725 TB cases notified in Paraguay from 2018 to 2022, 2,331 (17%) occurred among incarcerated individuals and 1,743 (12.7%) occurred among self-identified Indigenous individuals. In 2022, the relative risk of TB was 87 and 6.4 among the incarcerated and Indigenous populations, compared with the non-incarcerated and non-Indigenous populations respectively. We found significant heterogeneity in TB incidence across Paraguays 17 departments. Our findings highlight the urgency of expanding access to TB diagnosis, treatment, and prevention in populations at heightened risk of TB in Paraguay.
Authors: Katharine S. Walter, A. Medina, J. Sussman, N. Sosa, M. Valdez, J. R. Andrews, J. Croda, G. E. Sanabria, G. Sequera, S. Aguirre
Last Update: 2024-06-01 00:00:00
Language: English
Source URL: https://www.medrxiv.org/content/10.1101/2024.05.31.24308287
Source PDF: https://www.medrxiv.org/content/10.1101/2024.05.31.24308287.full.pdf
Licence: https://creativecommons.org/licenses/by/4.0/
Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.
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