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The Dance of Particles: Noise and Motion

Discover how noise influences particle movement in biological systems.

Saloni Saxena, Marko Popović, Frank Jülicher

― 6 min read


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Imagine a small particle trying to move through a landscape filled with hills and valleys, much like a ball rolling over a bumpy surface. This is somewhat similar to what happens in certain biological systems, where things are not always calm and stable. In these systems, particles often find themselves in a state that is not balanced—that is, they are always in motion due to various external influences. This paper explores how such a particle behaves when subjected to different types of Noise in its environment.

What is a Ratchet?

Let’s start by understanding what a “ratchet” is. You might know it as the device that makes a clicking sound when you turn it, but in this context, it’s a model system where a particle moves back and forth in a series of potential wells. Think of the particle like a kid on a seesaw—trying to balance but always getting a little help from the external push of noise, which in this case might be likened to a gust of wind.

In the ratchet model, the wells are like little cups that the particle can settle into. But due to their design, the particle prefers to move in one direction. This leads to a steady flow of particles, even when the system appears to be at rest, creating a non-zero current.

Exploring the Particle’s Journey

Now, what happens when we introduce colored noise? Colored noise is a fancy term for random fluctuations that are not just haphazard but have a pattern, a bit like a song with a rhythm. This noise can change in intensity and modify how the particle moves in the ratchet.

The study looks at two scenarios:

  1. Resetting Noise: In this scenario, whenever the particle hops into a new well, the noise resets to a specific value. You can think of it like starting over every time you take a step on a dance floor. At first, it seems intuitive that the more the noise changes, the more the particle must also bounce around. Surprisingly, as the noise becomes more persistent (the correlation time increases), the overall movement tends to slow down. Instead of dancing faster as expected, the particle is kind of stuck in its groove, moving less as the noise stays around longer.

  2. Free Evolving Noise: In the second case, the noise is allowed to evolve without resetting at each jump. Here, the results turn around a bit. The particle finds a rhythm as the noise varies, making it easier for it to hop upward against the tilt of the potential. Under these conditions, there is indeed a sweet spot—an optimal noise strength where the particle can move with the most energy.

The Role of Biological Systems

These experiments and models have real-world implications, especially when thinking about biological systems like Tissues in our bodies. Just as the particle dances in the ratchet, Cells in a tissue are constantly moving and reshaping themselves. They use energy from the environment to stay active. This keeps them far from a peaceful, balanced state.

When cells interact—whether they’re dividing, stretching, or changing shape—it can lead to behaviors that mimic the particle in the ratchet. For example, when two neighboring cells connect or disconnect, they experience what’s called a T1 transition. Picture this: two friends holding hands, but then one lets go, and they both shift positions to stay connected to someone else. This can create tensions within the tissue, leading to motion in preferred directions.

Understanding Motion in Tissues

Just as the ratchet utilizes noise to guide particle movement, tissues experience similar push-and-pull dynamics due to collective cell movements. Chemical signals between cells encourage them to grow or move, leading to a sort of choreography that keeps everything in motion.

The researchers construct a toy model that uses these concepts to help us better grasp how tissues work. By using a sawtooth potential in the ratchet model, they mimic the energy landscape that cells navigate.

The Vertex Model Explained

In order to understand how the cells interact, we can look at what’s known as the vertex model. Imagine each cell as a shape with corners, and these shapes are all connected at edges or bonds. The tension within these bonds affects how the cells behave. If a bond tightens or loosens, the cell might stretch or contract, similar to a rubber band.

As these cells change shape, the entire tissue behaves in a way that can be mathematically modeled. The vertex model captures these dynamics well since it considers various forces at play, including the area and perimeter of each cell.

The Two Cases of Particle Movement

To sum it up, the study investigates two main ways the particle can hop through its potential:

1. Resetting at Jumps

Every time the particle hops, it hits a reset button on the noise. This scenario reveals a curious trend: while the current is negative (meaning the average movement is against the potential gradient), the current seems to drop as noise correlation time increases. Those jumps are happening, but not as effectively as one might hope.

2. No Resetting

In this second scenario, the particle can continue moving without resetting. The analysis here uncovers that a certain level of noise can actually benefit the particle’s movement, resulting in effective upward motion. It seems that the longer the particle can be influenced by the noise, the more it can navigate through challenges, emphasizing the importance of not just the noise, but how it plays out over time.

The Interest of Biological Matter

Why does all this matter? Understanding how particles and cells operate under noise helps us learn more about active matter, including tissues in the body. For instance, if scientists can manipulate noise parameters in cell models, they might gain insights into diseases where tissue dynamics go awry.

In our everyday lives, we often see how small environmental changes create ripples of influence on larger systems. Whether it's a gust of wind moving a leaf or the sound of a drum influencing dancers, the principles examined here apply broadly to numerous scenarios.

Conclusion

In closing, this exploration into the dynamics of particles in a correlated ratchet reveals fascinating insights that go beyond the confines of physics. It touches on a deeper understanding of how life in tissues operates, driven by noise and interactions.

The journey of a single particle in a ratchet is much like our own lives—filled with bumps, resets, and a dance between chaos and order. The next time you see a leaf flutter in the wind or observe a group of cells dividing, remember that there’s a whole world of unseen dynamics at play, orchestrating a symphony of movement and change.

Who knew that particles could teach us so much about life—and how we might one day dance our way to better health?

Original Source

Title: Particle transport in a correlated ratchet

Abstract: One of the many measures of the non-equilibrium nature of a system is the existence of a non-zero steady state current which is especially relevant for many biological systems. To this end, we study the non-equilibrium dynamics of a particle moving in a tilted colored noise ratchet in two different situations. In the first, the colored noise variable is reset to a specific value every time the particle transitions from one well to another in the ratchet. Contrary to intuition, we find that the current magnitude decreases as the correlation time of the noise increases, and increases monotonically with noise strength. The average displacement of the particle is against the tilt, which implies that the particle performs work. We then consider a variation of the same problem in which the colored noise process is allowed to evolve freely without any resetting at the transitions. Again, the average displacement is against the potential. However, the current magnitude increases with the correlation time, and there is an optimal noise strength that maximizes the current magnitude. Finally, we provide quantitative arguments to explain these findings and their relevance to active biological matter such as tissues.

Authors: Saloni Saxena, Marko Popović, Frank Jülicher

Last Update: 2024-12-12 00:00:00

Language: English

Source URL: https://arxiv.org/abs/2412.09103

Source PDF: https://arxiv.org/pdf/2412.09103

Licence: https://creativecommons.org/licenses/by/4.0/

Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.

Thank you to arxiv for use of its open access interoperability.

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