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Rethinking Stroke Recovery: The Role of Reactive Balance Training

A study investigates how balance training can aid stroke recovery.

Augustine J. Devasahayam, Azadeh Barzideh, David Jagroop, Cynthia Danells, Elizabeth L. Inness, Susan Marzolini, Sunitha Mathur, Paul Oh, Avril Mansfield

― 6 min read


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Stroke is a significant health issue in Canada, affecting many people and their ability to live independently. In 2013, about 405,000 Canadians were living with the aftermath of a stroke, and this number is expected to grow to 726,000 by 2038. That's a huge number, like filling up a hockey arena multiple times! This rise in stroke cases comes with an increased burden on the healthcare system, which has to provide care for more people.

Transitioning Care After a Stroke

After a stroke, patients often find themselves in one of several care situations. Some go home on their own, while others might need some home care help. Some are sent to rehab centers to regain their strength and skills, and a few might end up in long-term care facilities. The care path depends on how well the patient is recovering physically, mentally, and socially. Sadly, many stroke survivors will face falls, with data showing that between one and six months after the event, up to 37% of these individuals might take a tumble. The chance of falling increases even more, reaching as high as 73% within a year.

The Role of Balance in Recovery

Balance is crucial for everyone, but it's especially important for those who have had a stroke. If someone struggles with balance after a stroke, they are more likely to injure themselves in a fall. And as we all know, that can lead to even more challenges, such as further disability or higher healthcare costs. That's where something called Reactive Balance Training (RBT) comes in. It aims to improve how quickly someone can react to losing their balance, helping reduce the risk of falls after they leave inpatient care.

What's fascinating is that RBT can also benefit other physical fitness areas, like aerobic capacity and Muscle Strength. However, research on RBT's effectiveness in improving these areas for stroke patients hasn't been done yet.

Study Purpose and Design

This leads us to a recent study that set out to determine how effective RBT was in improving fitness compared to traditional aerobic and strength training (AST). The study took a closer look at how RBT affects Cardiorespiratory Fitness and muscle strength in those living with chronic stroke.

The interim results were taken from a pilot study that aimed to identify the right sample size for a larger trial. It also wanted to see if they could successfully recruit enough participants. This pilot used a randomized controlled trial design, which means participants were randomly assigned to either RBT or AST. To keep things fair, assessors who measured outcomes were kept in the dark about which group participants were in.

The study took a hit due to the COVID-19 pandemic, which caused delays and disruptions for about a year. Participants were recruited through various methods, such as previous studies, referrals from rehabilitation centers, and local advertisements. To qualify, participants had to be diagnosed with chronic stroke, at least 20 years old, and capable of standing independently for a short time.

Participants and Exclusions

As with any study, there were criteria for who could and could not participate. People with certain conditions, such as severe osteoporosis or uncontrolled health issues, were left out to protect their well-being during the study. Once they ensured that all participants were safe and understood the study, they gave their consent to join.

The exercise interventions were led by a physiotherapist. They involved three, hour-long exercise sessions each week for 12 weeks. Those in the AST group engaged in a mix of aerobic and strength training, while the RBT group practiced exercises designed to improve balance and reaction times.

Randomization and Recruitment

Participants were assigned to groups using a random allocation method to ensure fairness. This way, everyone had an equal chance of being in either group. They also tracked how well each group progressed during the study.

The plan was to recruit at least 20 participants for the pilot study. However, the pandemic caused significant recruitment challenges, leading to fewer participants than expected. In total, 28 participants joined, with some dropping out or withdrawing from the study due to various reasons.

Evaluating Feasibility

One of the primary aims of the pilot study was to see if it was possible to recruit enough participants for a larger trial. This included tracking how many signed up, how many withdrew, and whether the study could proceed with the revised sample size. It also looked at how well participants stuck to their training and if any data was missing.

Intervention adherence was measured by checking how many sessions each participant attended, how long they exercised, and how many perturbations they faced during RBT sessions. In the end, 12 participants were in the AST group and 11 in the RBT group.

Results of the Pilot Study

After analyzing how many sessions participants attended, researchers saw that adherence was reasonably high. The AST group managed to attend about 30 sessions on average, while the RBT group attended just under 24 sessions. Life happens, though, and attendance could dip due to weather, illness, or other schedule conflicts.

When it came to collecting data, they found some missing numbers, but nothing too alarming. That said, the study showed that while the interventions were generally well-received, the large sample size needed for the main trial made it tough to proceed.

Aiming for Improvement

The pilot study laid the groundwork for understanding the effectiveness of RBT. While both groups showed improvements in specific outcomes, the required sample size for the main trial increased significantly compared to initial estimates. This was mostly due to the variability in results.

Recruiting enough participants for stroke rehabilitation trials can be a challenge. Many studies end up falling short of their recruitment goals, and this one was no different. With pandemic restrictions and other hurdles, these challenges became even more pronounced.

Despite the bumps in the road, the study saw notable improvements in participants' fitness and balance skills. These results give hope that RBT could be a beneficial option for improving recovery after a stroke.

Conclusion: Looking Ahead

In summary, the pilot study provided valuable insights into the feasibility of a larger trial. It highlighted both the challenges and potential of RBT in enhancing fitness for stroke survivors. While the larger trial might not be possible under the current conditions, the findings indicate that RBT could safely help improve physical capacity in individuals who have experienced a stroke.

Future studies will need to consider alternative designs, better recruitment strategies, and possibly work across multiple sites to tackle these issues head-on. As we look to improve stroke rehabilitation methods, RBT may hold promise in helping individuals regain their balance and confidence in everyday life. Because, let's face it, staying upright is a pretty big deal!

Original Source

Title: The effects of reactive balance training on cardiorespiratory fitness and muscle strength: a pilot randomized controlled trial

Abstract: BackgroundReactive balance training (RBT) may improve multiple components of physical fitness, including aerobic capacity and muscle strength. However, there have been no studies examining its effects on these factors in people with stroke. ObjectivesThe objectives of this pilot study were to determine the feasibility of a non-inferiority randomized controlled trial, comparing aerobic and strength training (AST) and RBT, considering sample size (primary objective), rates of accrual and withdrawal, intervention adherence, missing data, preliminary effects, and harms (secondary objectives). MethodsPeople who were at least six months post-stroke and could stand independently for >30 seconds were recruited. Peak oxygen consumption [Formula] was measured by cardiopulmonary exercise test. Peak isokinetic torques for knee extension and flexion were measured by dynamometer. ResultsTwenty-three participants (6 women) were randomized into AST and RBT groups. Four-hundred participants per group were estimated to be required for the main trial considering [Formula] and peak isokinetic torque as primary outcomes. Rates of accrual and withdrawal were 2 participants for every quarter and 30%, respectively. On average, AST participants attended 29.6/36 sessions (range: 18-36) and RBT participants attended 23.5/36 sessions (range: 1-35). Data were missing for [Formula] (n=2) and ABC scale (n=1) as participants declined testing. [Formula] and peak knee extension torque of more-affected legs improved post-intervention in both groups. Ten adverse events related to study interventions resolved without medical attention. ConclusionProgressing to a definitive single-site trial is not feasible given the large required sample size, low accrual, and high withdrawal rates. Trial registrationNCT04042961

Authors: Augustine J. Devasahayam, Azadeh Barzideh, David Jagroop, Cynthia Danells, Elizabeth L. Inness, Susan Marzolini, Sunitha Mathur, Paul Oh, Avril Mansfield

Last Update: 2024-12-16 00:00:00

Language: English

Source URL: https://www.medrxiv.org/content/10.1101/2024.12.16.24319109

Source PDF: https://www.medrxiv.org/content/10.1101/2024.12.16.24319109.full.pdf

Licence: https://creativecommons.org/licenses/by/4.0/

Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.

Thank you to medrxiv for use of its open access interoperability.

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