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COVID-19 and Stroke: A Hidden Danger

Learn about the increased stroke risk linked to COVID-19, especially for older adults.

Emilia H. Koumans, Julia Raykin, Tegan K. Boehmer, Sharon Saydah, Jennifer Wiltz, Shikha Garg, Carol E. DeSantis, Thomas W. Carton, Lindsay G. Cowell, Deepika Thacker, Jonathan Arnold, Sonja A. Rasmussen, Samantha J. Smith, Kimberly Barrett, Christine Draper, Fátima Coronado, Elizabeth A. Lundeen, Rebecca C. Woodruff, Jason P. Block

― 5 min read


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COVID-19, the disease caused by the coronavirus, has shown it has more tricks up its sleeve than just coughs and fevers. One of the surprising side effects is an increased risk of stroke, especially among older adults. This article will break down what we know about this risky relationship, how it compares to Influenza, and what it means for those who are 65 years or older.

What Is a Stroke?

A stroke happens when blood flow to part of the brain is cut off, leading to brain damage. Think of it as a traffic jam in the brain, where some roads are blocked and the emergency vehicles (or oxygen) can’t get through. There are different types of Strokes, but the acute ischemic stroke (AIS) is the most common. This type results from a blood clot blocking the flow of blood.

COVID-19: Not Just a Respiratory Illness

While COVID-19 primarily affects the lungs, it has also been linked to a host of other health issues. Research has found that COVID-19 can increase the risk of thrombotic events, which sounds fancy but basically means the formation of blood clots, leading to strokes and other problems. The risk of having a stroke after getting sick with COVID-19 can range from as low as half a percent to as high as over 8%, depending on how severe the illness is.

Who Is Most at Risk?

Older adults, particularly those aged 65 years and older, face a higher risk of stroke if they contract COVID-19. The reasons for this are varied. Many older adults have underlying health issues—like high blood pressure, diabetes, or heart problems—which can complicate their recovery from COVID-19. These conditions may also contribute to the likelihood of experiencing a stroke after infection. Think of a snowball rolling downhill; as it gathers more snow, it becomes more challenging to stop. Similarly, having multiple health issues can amplify the risk.

The Timing of Strokes

If you contract COVID-19, you should pay attention in the days right after your diagnosis. Studies indicate that the risk of having a stroke is highest just after being diagnosed, particularly in the first week. So, if you feel like a balloon being inflated by a party clown, you might want to keep an eye out for any signs of trouble. When it comes to timing, it appears that strokes happen most in the 3 days leading up to and the 7 days following a COVID-19 diagnosis.

The Influenza Comparison

Just when you thought it was safe to enjoy the flu season, influenza has also been linked to an increased risk of stroke. While COVID-19 has been the star of the show lately, influenza is like that reliable supporting actor that can still cause serious health issues. The stroke risk with influenza may not be as high as with COVID-19; however, it still poses a risk, especially for older adults. It’s like comparing apples to oranges, only one apple can make you cough and the other can give you a headache.

Treating COVID-19 Patients

To combat the risk of strokes in Hospitalized COVID-19 patients, doctors often recommend blood thinners. These treatments, like heparin, work to prevent blood clots from forming. However, it’s not a one-size-fits-all situation. Some patients may be at a higher risk of bleeding, which complicates the use of these medications.

Understanding the Data

Researchers have investigated the incidence of AIS among COVID-19 and influenza patients using large health records databases. They looked at a massive number of patients aged 65 and older. The findings were sobering. For COVID-19 patients in one study group, about 2,559 individuals experienced strokes, whereas in another group, 3,757 reported strokes. The incidence rate of stroke was found to be 1,043 per 100,000 patients for COVID-19, while the rate for influenza was slightly lower at 664 per 100,000.

The Demographics

The studies showed interesting demographic trends. Both groups of patients with strokes had a fairly balanced representation of genders, with females making up about half of the cases. When it came to racial and ethnic makeup, non-Hispanic Whites represented a larger portion compared to non-Hispanic Blacks and Hispanics.

Hospitalization and Outcomes

For patients who experienced strokes, a significant number ended up being hospitalized. Many patients may have experienced other inflammatory conditions during and after their COVID-19 infection. It’s worth noting that around 10% of those who had strokes were discharged to hospice care, which underscores the seriousness of the situation.

Patterns of Stroke Occurrence

While both COVID-19 and influenza can lead to strokes, the timing of those strokes differs. For COVID-19 patients, most strokes occurred early on, often within the first week of being diagnosed. This pattern also held true for influenza, where the majority of strokes were recorded during the early days of the illness.

Takeaway for Older Adults

Older adults should be particularly careful during the flu and COVID-19 seasons. The combination of these illnesses with underlying conditions can elevate stroke risks. Getting vaccinations for both COVID-19 and the flu is an essential step to protect one’s health. In addition, managing chronic conditions like hypertension and diabetes can help keep stroke risks in check.

Recognizing Stroke Symptoms

It’s vital for older adults, their families, and caregivers to recognize the early signs of stroke. Symptoms can include sudden confusion, trouble speaking, weakness on one side of the body, and difficulty seeing. If someone shows these signs, it’s like pushing the panic button on a life raft—call for help immediately!

Conclusion

Both COVID-19 and influenza present significant health risks, particularly for older adults. The increased risk of stroke is a reminder that these viruses can cause more than just respiratory problems. Keeping an eye on health, managing chronic conditions, and being vigilant about the signs of stroke can make a significant difference. So, stay informed, stay safe, and remember: the sooner you act, the better the chances for a good outcome!

Original Source

Title: Incidence of acute ischemic stroke after COVID-19 or influenza among older adults, findings from PCORnet and HealthVerity, 2022

Abstract: BackgroundAlthough COVID-19 is a known risk factor for thrombotic conditions including embolism, stroke, and myocardial infarction, stroke incidence after implementation of thromboprophylaxis during COVID-19 hospitalization in 2021 and how incidence may differ from influenza is unknown. MethodsPCORnet and HealthVerity (HV) data assets were used to identify patients aged [≥]65 years with no prior stroke and COVID-19 or influenza during January 1-December 31, 2022, and AIS from 3 days before to 28 days after COVID-19 or influenza diagnosis. Overall demographic information (age [for HV], sex, race/ethnicity), underlying conditions, level of care, outcomes, and incidence were described and compared between those with early (-3 to 7 days from diagnosis date) and late (8 to 28 days) AIS. ResultsAmong 245,352 (PC) and 639,396 (HV) patients aged [≥]65 years with COVID-19, the incidence of ischemic stroke in the 3 days prior to 7 days after diagnosis of COVID-19 (PC: 962/100,000 and HV: 447/100,000) and influenza (PC: 589/100,000 and HV: 387/100,000) was significantly higher than in the 8 to 28 days after diagnosis (COVID PC: 81/100,000 and HV: 141/100,000)(influenza PC:75/100,000 and HV: 15/100,000)(all P

Authors: Emilia H. Koumans, Julia Raykin, Tegan K. Boehmer, Sharon Saydah, Jennifer Wiltz, Shikha Garg, Carol E. DeSantis, Thomas W. Carton, Lindsay G. Cowell, Deepika Thacker, Jonathan Arnold, Sonja A. Rasmussen, Samantha J. Smith, Kimberly Barrett, Christine Draper, Fátima Coronado, Elizabeth A. Lundeen, Rebecca C. Woodruff, Jason P. Block

Last Update: 2024-12-21 00:00:00

Language: English

Source URL: https://www.medrxiv.org/content/10.1101/2024.12.19.24318004

Source PDF: https://www.medrxiv.org/content/10.1101/2024.12.19.24318004.full.pdf

Licence: https://creativecommons.org/publicdomain/zero/1.0/

Changes: This summary was created with assistance from AI and may have inaccuracies. For accurate information, please refer to the original source documents linked here.

Thank you to medrxiv for use of its open access interoperability.

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